RESUMO
The study was carried out in dairy cows to elucidate whether treatment of clinical mastitis quarters with Spectramast® LC (ceftiofur hydrochloride, 125 mg, Zoetis) created a reason for discarding milk from adjacent untreated healthy quarters. The antibiotic was infused once daily in the affected mammary quarter for four days. Forty-nine cows were evaluated after diagnosis of clinical mastitis in three or fewer udder quarters. In all cases, quarters that did not receive treatment had milk samples collected one day after the end of treatment. All milk samples from untreated quarters were below the maximum permissible limit for the presence of antibiotic residues after analysis with the BetaStar S Combo test. Pharmacokinetic and pharmacodynamic characteristics may explain this finding. We conclude that it is feasible to use milk from untreated quarters of animals that have been treated with Spectramast® LC. We also reiterate the need to carry out tests with other pharmacological bases, and that the results found in this experiment cannot be extrapolated to other drugs.Dairy cattle have considerable importance in the development of the Brazilian economy, being directly linked to economic and social progress. In the first half of 2020, 12.1 billion liters of milk were produced in Brazil and in 2019, there was a new record of 25.01 billion liters produced (IBGE, 2020). This production comes from a wide variety of production systems, coming from smallholder farmers as well as from large companies that use the latest technologies available on the market. Dairy production is a complex activity. For one to obtain economical success, several aspects must be monitored. Maintaining the health of animals is a top priority, and the literature suggests that various diseases are a common challenge for dairy producers. Mastitis is the main disease that affects dairy cows, responsible for considerable economic loss and significant zootechnical and productive challenges (Ruegg, ). It is considered the second leading cause of cow culling in dairy herds, behind reproductive problems. Mastitis is characterized by infection of the mammary gland and may or may not occur with inflammation, generating changes in the mammary tissue and properties of the milk. It is classifield into clinical or subclinical mastitis, according to presence or absence of clinical signs, and into contagious or environmental based on the causative agent (Correa et al., ).
RESUMO
This study aimed to assess the effects of maternal protein supplementation and offspring sex (OS) on the intake parameters of the offspring. Forty-three Tabapuã cows were randomly allocated in the following treatments: protein supplementation (PS) during days 100-200 of gestation (RES, 5.5% total crude protein (CP), n = 2, or CON, 10% total CP, n = 19) and OS (females, n = 20; males, n = 23). The offspring were evaluated during the cow-calf (0-210 days), backgrounding (255-320 days), growing 1 (321-381 days), and growing 2 (382-445 days) phases. The CON offspring tended to present higher dry matter intake (DMI) at weaning (p = 0.06). The CON males presented lower digestibility of major diet components in the growing 2 phase (p ≤ 0.02). The CON offspring spent 52% more time per day eating supplements at 100 days and 17% less time in idleness at 210 days. The CON males spent 15 min more per day ruminating than RES males in the feedlot phase (p = 0.01). We concluded that protein supplementation over gestation alters the offspring feed intake pattern as a whole, while protein restriction promotes compensatory responses on nutrient digestibility in males.
